Central core disease in one of identical twins.

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Central core disease in one of identical twins.

A case of central core disease in one of identical twins is presented. The light and electron microscopic pathology is reviewed. We believe that these entities are not genetic in this sibship and may be an example of isolated maturational arrest of non-specific aetiology.

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Juberg R C, Hayward J R. A new familial syndrome of oral, cranial, and digital anomalies. J Pediatr 1969; 74: 755-62. 2 Nevin N C, Henry P, Thomas P T S. A case of the orocraniodigital (Juberg-Hayward) syndrome. J Med Genet 1981; 18: 478-80. 3 Savage D C L, Swift P G F, Johnston P G B, Goldie D J, Murphy D. Combined test of anterior pituitary function in children. Arch Dis Child 1978; 53: 301-4...

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A disease resembling childhood coeliac disease occurred in one of identical twins. When the twins were investigated at the age of 23 the initial diagnosis could not be substantiated but the twin who had been ill had selective IgA deficiency. Differences dating from early infancy may have been a result of the discordance for IgA deficiency. Thus in some patients environmental influences may be i...

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Genetically proven identical twin sisters with Alzheimer's disease are reported. Both sisters at the age of fifty years developed a dementing illness. Their mother and maternal grandmother developed at the same age a similar illness. It is suggested that in some cases of familial Alzheimer's disease the condition is inherited by a single mutant gene.

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1978

ISSN: 0022-3050

DOI: 10.1136/jnnp.41.7.659